Papel protetor da quinase ativada por adenosina monofosfato (AMPK) na progressão e severidade da nefrite tubulointersticial experimental.

Papel protetor da quinase ativada por adenosina monofosfato (AMPK) na progressão e severidade da nefrite tubulointersticial experimental.

Objetivamos investigar o papel da quinase ativada por adenosina monofosfato (AMPK) na doença renal crônica. Induzimos nefrite túbulo-intersticial (NTI) em camundongos C57BL/6 e LyzM-cre AMPKflox/flox através de ração com adenina, e tratamos com metformina (Met) 200 mg/kg/dia. Avaliamos ainda o efeit...

Full description

Bibliographic Details
Main Author:	Macêdo, Marina Barguil
Other Authors:	Câmara, Niels Olsen Saraiva
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2017
Subjects:	Adenosine monophosphate activated kinase (AMPK) Chronic kidney disease Doença renal crônica Immunometabolism Imunometabolismo Macrófagos Macrophages Metformin Metformina Quinase ativada por adenosina monofosfato (AMPK)
Online Access:	http://www.teses.usp.br/teses/disponiveis/42/42133/tde-31012018-140525/

Similar Items

Determinación de la respuesta bronquial a adenosina 5'monofosfato y de la concentración de óxido nítrico en aire exhalado en pacientes con colitis ulcerosa
by: Pérez Francés, Mª Carmen
Published: (2009)

Immunometabolic Activation of Invariant Natural Killer T Cells
by: Francesca A. Ververs, et al.
Published: (2018-05-01)

AMPK-Targeted Effector Networks in Mycobacterial Infection
by: Eun-Kyeong Jo, et al.
Published: (2019-03-01)

Potencial do treinamento físico para a prevenção de danos renais em camundongos: papel da proteína ativada por AMP (AMPK)
by: Cynthia Rodrigues Müller
Published: (2018)

Potencial do treinamento físico para a prevenção de danos renais em camundongos: papel da proteína ativada por AMP (AMPK)
by: Müller, Cynthia Rodrigues
Published: (2018)

Mecanismos de regulação da via iNOS-CD95L na eosinopoiese em modelo de cultura de medula óssea murina
by: França, Bianca de Luca
Published: (2016)

Análise de inosina-5'-monofosfato (5'-IMP) e seus derivados em diferentes músculos de bovinos, suínos e ovinos
by: Marta Suely Madruga
Published: (1997-08-01)

Irisin inhibits pancreatic cancer cell growth via the AMPK-mTOR pathway
by: Jiayu Liu, et al.
Published: (2018-10-01)

Plant-Derived Polyphenols Modulate Human Dendritic Cell Metabolism and Immune Function via AMPK-Dependent Induction of Heme Oxygenase-1
by: Nicole K. Campbell, et al.
Published: (2019-03-01)

Foam Cell Induction Activates AMPK but Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis
by: Nicholas D. LeBlond, et al.
Published: (2020-11-01)

Derivados de quinazolinas na inibição da adenosina quinase
by: Rodrigues, Fábio Henrique dos Santos, 1986-
Published: (2011)

Insights Into the Pathologic Roles and Regulation of Eukaryotic Elongation Factor-2 Kinase
by: Darby J. Ballard, et al.
Published: (2021-08-01)

Caracterização do efeito inibitorio de derivados aniquinazolinicos na atividade da adenosina quinase
by: Marin, Rodrigo Miguel
Published: (2007)

Is TAK1 a Direct Upstream Kinase of AMPK?
by: Dietbert Neumann
Published: (2018-08-01)

Metformin Had Potential to Increase Endocan Levels in STZ-Induced Diabetic Mice
by: Elmira Zolali, et al.
Published: (2020-06-01)

Estudo do efeito do inibidor da enzima adenosina desaminase, EHNA, sobre a enterite induzida pela toxina a do Clostridium difficile em alça ileal isolada de camundongos
by: Junqueira, Ana Flávia Torquato de Araújo
Published: (2012)

High hydrostatic pressure extract of mulberry leaves ameliorates hypercholesterolemia via modulating hepatic microRNA-33 expression and AMPK activity in high cholesterol diet fed rats
by: Eunyoung Lee, et al.
Published: (2021-05-01)

The Study of the Response of Fat Metabolism to Long-Term Energy Stress Based on Serum, Fatty Acid and Transcriptome Profiles in Yaks
by: Lin Xiong, et al.
Published: (2020-07-01)

Vitamin D Ameliorates Fat Accumulation with AMPK/SIRT1 Activity in C2C12 Skeletal Muscle Cells
by: Eugene Chang, et al.
Published: (2019-11-01)

Caffeic Acid Expands Anti-Tumor Effect of Metformin in Human Metastatic Cervical Carcinoma HTB-34 Cells: Implications of AMPK Activation and Impairment of Fatty Acids De Novo Biosynthesis
by: Malgorzata Tyszka-Czochara, et al.
Published: (2017-02-01)

Efeitos da adenosina e inosina sobre pleurisia e asma
by: Lapa, Fernanda da Rocha
Published: (2012)

Glucocorticoid and its effect on cardiac glucose utilization
by: Puthanveetil, Prasanth Nair
Published: (2009)

Glucocorticoid and its effect on cardiac glucose utilization
by: Puthanveetil, Prasanth Nair
Published: (2009)

Glucocorticoid and its effect on cardiac glucose utilization
by: Puthanveetil, Prasanth Nair
Published: (2009)

Over-expressions of <it>AMPK</it> subunits in ovarian carcinomas with significant clinical implications
by: Li Cuilan, et al.
Published: (2012-08-01)

Guanosina : uma nova abordagem do sistema purinérgico
by: Soares, Felix Alexandre Antunes
Published: (2007)

Guanosina : uma nova abordagem do sistema purinérgico
by: Soares, Felix Alexandre Antunes
Published: (2007)

Guanosina : uma nova abordagem do sistema purinérgico
by: Soares, Felix Alexandre Antunes
Published: (2007)

O uso da drotrecogina alfa ativada na prática clínica e as atuais evidências Drotrecogin alfa activated in clinical practice and the current evidences
by: Márcio Soares, et al.
Published: (2008-06-01)

Argamassas geopoliméricas à base de cinzas volantes álcali-ativadas contendo areia de fundição
by: A. S. de Vargas, et al.
Published: (2015-09-01)

Resposta terapêutica à drotrecogina alfa (ativada) em pacientes com sepse grave nas Unidades de Terapia Intensiva da regiãometropolitana do Recife
by: HECKCHER, Cristiano Augusto
Published: (2014)

Genetic and Environmental Factors that Mediate Survival of Prolonged Oxygen Deprivation in the Nematode Caenorhabditis Elegans
by: LaRue, Bobby Lee, Jr.
Published: (2010)

AMPK activation overcomes anti-EGFR antibody resistance induced by KRAS mutation in colorectal cancer
by: Hua Ye, et al.
Published: (2020-07-01)

Metformin revert insulin‐induced oxaliplatin resistance by activating mitochondrial apoptosis pathway in human colon cancer HCT116 cells
by: Chao Liu, et al.
Published: (2020-06-01)

Pharmacological Analyses of Protein Kinases Regulating Egg Maturation in Marine Nemertean Worms: A Review and Comparison with Mammalian Eggs
by: Alicia Marquardt, et al.
Published: (2010-08-01)

The effects of troglitazone and PMA on AMPK in HepG2 cells
by: Allen, Katherine
Published: (2016)

Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice
by: Nicholas D. LeBlond, et al.
Published: (2020-12-01)

1,25-Dihydroxyvitamin D Decreases Tertiary Butyl-Hydrogen Peroxide-Induced Oxidative Stress and Increases AMPK/SIRT1 Activation in C2C12 Muscle Cells
by: Eugene Chang
Published: (2019-10-01)

The role of SIRT1 in the pathogenesis of insulin resistance in skeletal muscle
by: Magdalena Stefanowicz, et al.
Published: (2015-01-01)

Iron deficiency causes a shift in AMP-activated protein kinase (AMPK) subunit composition in rat skeletal muscle
by: Merrill John F, et al.
Published: (2012-11-01)