Contribuição da via STIM1/Orai1 para as diferenças relacionadas ao sexo na entrada de cálcio em miócitos vasculares durante a hipertensão arterial.

Contribuição da via STIM1/Orai1 para as diferenças relacionadas ao sexo na entrada de cálcio em miócitos vasculares durante a hipertensão arterial.

Os distúrbios na regulação da concentração de cálcio (Ca2+) citoplasmático contribuem para a patogênese da hipertensão arterial. Evidências sugerem que as moléculas de interação estromal (STIM) atuam como sensores dos estoques intracelulares de Ca2+, enquanto as proteínas Orai representam as subunid...

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Bibliographic Details
Main Author:	Giachini, Fernanda Regina Casagrande
Other Authors:	Passaglia, Rita de Cassia Aleixo Tostes
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2010
Subjects:	Diferenças sexuais (Psicogênese) Disfunção vascular Hipertensão Hormônios sexuais Hypertension Orai1 Sex differences (Psychogenesis) Sex hormones STIM1 Vascular dysfunction
Online Access:	http://www.teses.usp.br/teses/disponiveis/42/42136/tde-28092010-170302/

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