Avaliação da expressão imunoistoquímica de PTEN, AKT fosforilada e receptor de androgênio em carcinomas de mama HER-2 positivos

Avaliação da expressão imunoistoquímica de PTEN, AKT fosforilada e receptor de androgênio em carcinomas de mama HER-2 positivos

INTRODUÇÃO: Os carcinomas HER-2 positivos representam cerca de 20- 30% de todos os tumores da mama e se caracterizam por curso clínico mais agressivo, com alta proliferação celular e resistência a apoptose, determinados por cascatas de sinalizações intracelulares, tais como a via PI3K/AKT. O trastuz...

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Bibliographic Details
Main Author:	Lin, Francini de Mattos Lima
Other Authors:	Carvalho, Filomena Marino
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2012
Subjects:	Androgen receptor Breast neoplasms Carcinoma apócrino molecular Immunohistochemistry Imunoistoquímica Molecular aprocrine carcinoma Neoplasias da mama Oncogene protein v-akt Proteína oncogênica v-akt PTEN fosfoidrolase PTEN phosphohydrolase Receptor androgênico Receptor do fator de crescimento epidérmico Receptor epidermal growth factor
Online Access:	http://www.teses.usp.br/teses/disponiveis/5/5139/tde-27022013-142349/

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