Desenvolvimento de anti-hTNFα terapêutico.

Desenvolvimento de anti-hTNFα terapêutico.

O objetivo do projeto foi desenvolver linhagens celulares para um anticorpo terapêutico anti-hTNFα e comprovar sua funcionalidade. Os genes anti-hTNFα foram clonados em células CHO para seleção da população estável mista, demonstrando expressão de anticorpo com reconhecimento de hT...

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Bibliographic Details
Main Author:	Luchese, Mateus Dalcin
Other Authors:	Moro, Ana Maria
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2016
Subjects:	Anticorpo terapêutico Autoimmunity Autoimunidade Biosimilar/biobetter Biossimilar/biossuperior Cell line generation Células CHO CHO cells Geração de linhagem celular Therapeutic antibody TNFα
Online Access:	http://www.teses.usp.br/teses/disponiveis/87/87131/tde-26082016-105426/

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