Análise do efeito do Prima-1 na expressão dos genes envolvidos na morte celular programada em linhagens de câncer de bexiga

Análise do efeito do Prima-1 na expressão dos genes envolvidos na morte celular programada em linhagens de câncer de bexiga

Introdução: O carcinoma urotelial de bexiga (CUB) é o segundo tumor mais frequente do trato urinário. A perda da função do p53 é a alteração mais conhecida do carcinoma urotelial de alto grau invasivo. Prima-1 é uma pequena molécula, a qual restaura a função do p53 mutado promovendo a morte celular...

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Bibliographic Details
Main Author:	Piantino, Camila Belfort
Other Authors:	Antunes, Alberto Azoubel
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2012
Subjects:	Apoptose Apoptosis Bladder urothelial carcinoma Carcinoma urotelial de bexiga Neoplasias urológicas p53 Prima-1 Urologic neoplasms
Online Access:	http://www.teses.usp.br/teses/disponiveis/5/5153/tde-25092012-090310/

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