Influência do Gene APE1/REF-1 nas Respostas Celulares das Linhagens de Glioblastoma ao Quimioterápico Temozolomida

Influência do Gene APE1/REF-1 nas Respostas Celulares das Linhagens de Glioblastoma ao Quimioterápico Temozolomida

A proteína APE1 (do inglêsApurinic/Apyrimidinicendonuclease 1/ Redox Factor-1 - APE1/REF-1) é uma enzima multifuncional, cuja expressão encontra-se frequentemente aumentada em gliomas. Além de apresentar atividade no reparo por excisão de base (BER), o gene APE1 também atua como fator de redução, ma...

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Bibliographic Details
Main Author:	Montaldi, Ana Paula de Lima
Other Authors:	Hojo, Elza Tiemi Sakamoto
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2013
Subjects:	APE1/REF-1 gene Base excision repair DNA damage responses Gene APE1/REF-1.2 Glioblastoma Reparo por excisão de base Respostas a danos no DNA siRNA Temozolomida Temozolomide
Online Access:	http://www.teses.usp.br/teses/disponiveis/17/17135/tde-24102013-103232/

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