Estudo dos níveis plasmáticos de miR-208a na cardiotoxicidade de pacientes submetidos à quimioterapia com antraciclina

Estudo dos níveis plasmáticos de miR-208a na cardiotoxicidade de pacientes submetidos à quimioterapia com antraciclina

INTRODUÇÃO: Cardiotoxicidade é frequentemente associada ao uso crônico de doxorubicina (DOX) podendo levar a cardiomiopatia e insuficiência cardíaca. A identificação de miRNAs cardiotoxicidade-específicos e seu potencial como biomarcadores poderia fornecer uma ferramenta prognostica valiosa e uma po...

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Bibliographic Details
Main Author:	Rigaud, Vagner Oliveira Carvalho
Other Authors:	Bocchi, Edimar Alcides
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2016
Subjects:	Anthracyclines Antraciclina Biomarcadores Biomarkers Breast neoplasms Cardiotoxicidade Cardiotoxicity Doxorrubicina Doxorubicin MicroRNA Neoplasias de mama
Online Access:	http://www.teses.usp.br/teses/disponiveis/5/5131/tde-20092016-163304/

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