O cluster de microRNAs miR-17-92 e seus alvos na oncogênese tiroidiana: influência de BRAFT1799A e de iodo.

O cluster de microRNAs miR-17-92 e seus alvos na oncogênese tiroidiana: influência de BRAFT1799A e de iodo.

O excesso de iodo inibe a proliferação celular e secreção hormonal, enquanto retarda os efeitos oncogênicos da ativação de RET/PTC3 na célula folicular tiroidiana. A mutação BRAF (T1799A) é a mais prevalente no câncer de tiroide, e modelo transgênico desenvolve câncer que progride para histotipo agr...

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Bibliographic Details
Main Author:	Fuziwara, Cesar Seigi
Other Authors:	Kimura, Edna Teruko
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2014
Subjects:	BRAF Câncer de tiroide Iodine Iodo MicroRNA miR-17-92 Smad4 Thyroid cancer
Online Access:	http://www.teses.usp.br/teses/disponiveis/42/42134/tde-19112014-162309/

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