Prospecção de novas moléculas naturais e sintéticas na inibição in vitro da arginase recombinante de Leishmania (Leishmania) amazonensis

Prospecção de novas moléculas naturais e sintéticas na inibição in vitro da arginase recombinante de Leishmania (Leishmania) amazonensis

As leishmanioses constituem um complexo de doenças causadas por protozoários do gênero Leishmania. São transmitidas pela picada de fêmeas parasitadas do gênero Phlebotomus e/ou Lutzomyia. A leishmaniose é uma doença zoonótica que afeta mais de 12 milhões de pessoas no mundo, e constituem uma preocup...

Full description

Bibliographic Details
Main Author:	Come, Júlio Abel Alfredo dos Santos Simone
Other Authors:	Silva, Edson Roberto da
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2019
Subjects:	Leishmania amazonensis Arginase Arginase inhibitors Inibidores de arginase Poliaminas Polyamines Thiosemicarbazide Tiosemicarbazida
Online Access:	http://www.teses.usp.br/teses/disponiveis/74/74135/tde-19082019-104846/

Similar Items

Cinnamides Target <i>Leishmania amazonensis</i> Arginase Selectively
by: Edson Roberto da Silva, et al.
Published: (2020-11-01)

Aspectos imunopatogênicos da leishmaniose cutânea difusa: fatores da leishmania e do hospedeiro
by: Costa, Jaqueline França
Published: (2013)

Inibição da arginase de Leishmania por frações do extrato etanólico de Cecropia pachystachya
by: Cruz, Ebenézer de Mello
Published: (2012)

Kinetoplastid membrane protein-11 exacerbates infection with Leishmania amazonensis in murine macrophages
by: Daniel Ignacchiti Lacerda, et al.
Published: (2012-03-01)

A relação arginase-óxido nítrico na infecção experimental por Leishmania braziliensis
by: Santiago, Rômulo Carvalho
Published: (2013)

Relação entre a localização celular da enzima arginase de Leishmania (Leishmania) amazonensis e seu papel na infecção de macrófagos murinos
by: Maria Fernanda Laranjeira da Silva
Published: (2010)

Relação entre a localização celular da enzima arginase de Leishmania (Leishmania) amazonensis e seu papel na infecção de macrófagos murinos
by: Silva, Maria Fernanda Laranjeira da
Published: (2010)

Arginase Activity and Its Effects on Pathogenesis of Leishmania
by: Alireza Badirzadeh
Published: (2019-09-01)

Identification of Chalcone Derivatives as Inhibitors of Leishmania infantum Arginase and Promising Antileishmanial Agents
by: Andreza R. Garcia, et al.
Published: (2021-01-01)

The role of parasite-derived arginase in murine Leishmania major
by: Muleme, Helen
Published: (2010)

The role of parasite-derived arginase in murine Leishmania major
by: Muleme, Helen
Published: (2010)

Arginase Isoform Expression in Chronic Rhinosinusitis
by: Diana Vlad, et al.
Published: (2019-11-01)

The role of Leishmania proteophosphoglycans in sand fly transmission and infection of the mammalian host.
by: Matthew Edward Rogers
Published: (2012-06-01)

Estudo da atividade inibitória de extratos vegetais, flavonoides e derivados do ácido cafeico sobre a enzima arginase de Leishmania (Leishmania) amazonensis
by: João Francisco Lucon Junior
Published: (2016)

Estudo da atividade inibitória de extratos vegetais, flavonoides e derivados do ácido cafeico sobre a enzima arginase de Leishmania (Leishmania) amazonensis
by: Lucon Junior, João Francisco
Published: (2016)

Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances
by: Andreza R. Garcia, et al.
Published: (2019-01-01)

l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis
by: Abhishek Mandal, et al.
Published: (2017-07-01)

Corrigendum: l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis
by: Abhishek Mandal, et al.
Published: (2020-01-01)

Effect of Rosuvastatin on Arginase Enzyme Activity and Polyamine Production in Experimental Breast Cancer
by: Hakan Erbaş, et al.
Published: (2015-03-01)

Natural Products That Target the Arginase in <i>Leishmania</i> Parasites Hold Therapeutic Promise
by: Nicola S. Carter, et al.
Published: (2021-01-01)

Estudo da ação do extrato da planta Stachytarpheta cayennensis (Rich.) Vahl. (Gervão roxo) e compostos naturais sobre a enzima arginase de Leishmania (Leishmania) amazonensis
by: Amanda Maria Oliveira e Sá
Published: (2016)

Estudo da ação do extrato da planta Stachytarpheta cayennensis (Rich.) Vahl. (Gervão roxo) e compostos naturais sobre a enzima arginase de Leishmania (Leishmania) amazonensis
by: Sá, Amanda Maria Oliveira e
Published: (2016)

Tianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation of Arginase-Ornithine Pathway
by: Lili Zhang, et al.
Published: (2021-04-01)

The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis in the golden hamster model A atividade da azitromicina contra a Leishmania (Viannia) braziliensis e a Leishmania (Leishmania) amazonensis no modelo golden hamster
by: Ángel Sinagra, et al.
Published: (2007-12-01)

Avaliação do processo autofágico de macrófagos infectados com Leishmania amazonensis
by: Cyrino, Larissa Tavares
Published: (2011)

Inhibition of arginase modulates T-cell response in the tumor microenvironment of lung carcinoma
by: Anna Sosnowska, et al.
Published: (2021-01-01)

Melatonin and Leishmania amazonensis Infection Altered miR-294, miR-30e, and miR-302d Impacting on Tnf, Mcp-1, and Nos2 Expression
by: Juliane Cristina Ribeiro Fernandes, et al.
Published: (2019-03-01)

Arginase as a Potential Biomarker of Disease Progression: A Molecular Imaging Perspective
by: Gonçalo S. Clemente, et al.
Published: (2020-07-01)

Hypoxic Proliferation of Osteosarcoma Cells Depends on Arginase II
by: Bhuvana A. Setty, et al.
Published: (2016-08-01)

An epidermal-specific role for arginase1 during cutaneous wound repair
by: Crompton, R.A., et al.
Published: (2021)

Arginase Pathway in Acute Retina and Brain Injury: Therapeutic Opportunities and Unexplored Avenues
by: Abdelrahman Y. Fouda, et al.
Published: (2020-03-01)

PHARMACOLOGICAL EFFICACY OF AN INHIBITOR OF ARGINASE-2 KUD975 WITH L-NAME-INDUCED ENDOTHELIAL DYSFUNCTION
by: Konstantin Kudryavtsev, et al.
Published: (2017-03-01)

Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags
by: Luciana Girotto Gentil, et al.
Published: (2007-09-01)

Imunidade e envelhecimento : avaliação da produção de arginase e sintase do óxido nítrico por macrófagos de camundongos
by: Cecilio, Carla Aparecida, 1967-
Published: (2011)

The role of complement in the early phase of Leishmania (Leishmania) amazonensis infection in BALB/c mice
by: M.D. Laurenti, et al.
Published: (2004-03-01)

Role of Leishmania (Leishmania) amazonensis amastigote glycosphingolipids in macrophage infectivity
by: A.K. Tanaka, et al.
Published: (2007-06-01)

Characteristics of Arginase from the Terebellid Polychaete Pista Pacifica Berkeley
by: O'Malley, Karen Laurel
Published: (1973)

ASOTHEMIA EFFECT UPON THE LIVER ARGINASE ACTIVITY IN THE ACUTE KIDNEY DAMAGE
by: Jelena Djordjevic, et al.
Published: (2002-07-01)

Histopatologia da forma localizada de leishmaniose cutânea por Leishmania (Leishmania) amazonensis Histopathology of the localized form of cutaneous leishmaniasis due to Leishmania (Leishmania) amazonensis
by: Mário A. P. Moraes, et al.
Published: (1994-10-01)

Action of pentoxifylline on experimental cutaneous leishmaniasis due to Leishmania (Leishmania) amazonensis
by: Thiago de Sá Oliveira, et al.
Published: (2000-08-01)

Cannot write session to /tmp/vufind_sessions/sess_vq9jf93tu69geen36sr0vnmgud