Efeito da atorvastatina sobre a atividade funcional e expressão de transportadores de membrana do tipo ABC e SLC

Efeito da atorvastatina sobre a atividade funcional e expressão de transportadores de membrana do tipo ABC e SLC

Os transportadores de membrana do tipo ATP Binding Cassette (ABC) e solute carriers (SLC) regulam a homeostase intracelular de fármacos, modificando a biodisponibilidade e possivelmente a eficácia terapêutica. A variabilidade na resposta a hipolipemiantes, como as vastatinas, tem sido associada a vá...

Full description

Bibliographic Details
Main Author:	Rodrigues, Alice Cristina
Other Authors:	Hirata, Rosario Dominguez Crespo
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2008
Subjects:	ABC transporters Atorvastatin Atorvastatina Caco-2 CMSP HepG2 Hipercolesterolemia Hypercholesterolemia Lipídeos Lipids PBMCs SLC transporters Transportadores ABC Transportadores SLC
Online Access:	http://www.teses.usp.br/teses/disponiveis/9/9136/tde-19052009-200620/

Similar Items

Efeito da atorvastatina sobre a atividade funcional e expressão de transportadores de membrana do tipo ABC e SLC
by: Alice Cristina Rodrigues
Published: (2008)

Genetic heterogeneity in the apolipoprotein C-III promoter and effects of insulin
by: Geesje M. Dallinga-Thie, et al.
Published: (2001-09-01)

Hepatitis B virus induces G1 phase arrest by regulating cell cycle genes in HepG2.2.15 cells
by: Zhang Chong, et al.
Published: (2011-05-01)

Differential expression of several drug transporter genes in HepG2 and Huh-7 cell lines
by: Melva Louisa, et al.
Published: (2016-01-01)

Implications of enhanced effectiveness of vincristine sulfate/ε-viniferin combination compared to vincristine sulfate only on HepG2 cells
by: Filiz Özdemir, et al.
Published: (2016-12-01)

In vitro and in vivo evaluation of novel NGR-modified liposomes containing brucine
by: Li S, et al.
Published: (2017-08-01)

IL-6 İlavesi HEPG2 Hücrelerinde Kaspaz Aktivitelerini Nasıl Etkiler?
by: Burcu Menekşe BALKAN, et al.
Published: (2017-12-01)

Contribution à la formulation et à l'évaluation de liposomes d'ATP
by: Vincourt-Vitse, Véronique
Published: (2012)

Quantificação de lesões em DNA e RNA em cultura de células expostas a tetraidrofurano
by: Carla Fernanda Baquedano França
Published: (2012)

Isolamento e identificacao da arctigenina a partir dos frutos da Arctium lappa L. e avaliacao de atividade citotoxica in vitro e hepatoprotetora em ratos
by: Teixeira, Renan Salgado
Published: (2016)

Quantificação de lesões em DNA e RNA em cultura de células expostas a tetraidrofurano
by: França, Carla Fernanda Baquedano
Published: (2012)

Regulation of hypoxia inducible factor-1α expression by the alteration of redox status in HepG2 cells
by: Zhang Wu-kui, et al.
Published: (2011-05-01)

Potential Cytotoxic Activity of Psephellus pyrrhoblepharus Extracts
by: Pelin Taştan, et al.
Published: (2017-11-01)

Evaluation of the cytotoxic anticancer effect of polysaccharide of Nepeta septemcrenata
by: Sawsan Ahmed Nasr, et al.
Published: (2021-09-01)

In vitro study on the mechanisms of action of a novel phytotherapeutic compound against human hepatoma cells
by: Francesco Marotta, et al.
Published: (2007-04-01)

Hydrolytic Fate of 3/15-Acetyldeoxynivalenol in Humans: Specific Deacetylation by the Small Intestine and Liver Revealed Using in Vitro and ex Vivo Approaches
by: El Hassan Ajandouz, et al.
Published: (2016-07-01)

Absorption and Metabolism of Phenolics from Digests of Polyphenol-Rich Potato Extracts Using the Caco-2/HepG2 Co-Culture System
by: Shima Sadeghi Ekbatan, et al.
Published: (2018-01-01)

Wheat bran feruloyl oligosaccharides ameliorate AAPH-induced oxidative stress in HepG2 cells via Nrf2 signalling
by: Huijuan Zhang, et al.
Published: (2016-08-01)

Targeting MRP2 in HepG2 Cells Using the CRISPR-Cas9 System to Reverse Oxaliplatin Resistance
by: Zou, Ying
Published: (2019)

Investigation of Apoptotic Effect of Sinapic Acid in Hep3B and HepG2 Human Hepatocellular Carcinoma Cells
by: Canan Eroğlu, et al.
Published: (2017-11-01)

Radio-sensitizing effect of a cocktail of phytochemicals on HepG2 cell proliferation, motility and survival
by: Mohamed E. Abdraboh, et al.
Published: (2020-11-01)

Piceatannol attenuates fat accumulation and oxidative stress in steatosis-induced HepG2 cells
by: Jason Szuhao Yang, et al.
Published: (2020-11-01)

In vitro hepatoprotective activity of a polyherbal formulation on HepG2 cell line
by: Bibhuti Nath Bhatt, et al.
Published: (2017-01-01)

Cytotoxic activities of Ganoderma lucidum ethanol extract against HepG2 cell line
by: Kannan Mohan, et al.
Published: (2016-09-01)

A Multiwell Electrochemical Biosensor for Real-Time Monitoring of the Behavioural Changes of Cells in Vitro
by: Daman J. Adlam, et al.
Published: (2010-04-01)

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents in HepG-2 Cell Line
by: Weijie Xu, et al.
Published: (2017-03-01)

Mercury Induces Cytotoxicity and Transcriptionally Activates Stress Genes in Human Liver Carcinoma (HepG2) Cells
by: Elaine Shen, et al.
Published: (2002-09-01)

Identification of the chemical constituents of aqueous and alcoholic Glycyrrhiza glabra root extracts and its comparative apoptotic study against human hepatocarcinoma cell line
by: Nima Rezaiyan Gharagozlu, et al.
Published: (2019-03-01)

Nanoceria Attenuated High Glucose-Induced Oxidative Damage in HepG2 Cells
by: Mohammad Shokrzadeh, et al.
Published: (2016-04-01)

Effect of estradiol and bisphenol A on human hepatoblastoma cell viability and telomerase activity
by: B.L. Xu, et al.
Published: (2015-11-01)

Cytotoxicity and Transcriptional Activation of Stress Genes in Human Liver Carcinoma (HepG2) Cells Exposed to Iprodione
by: Paul B. Tchounwou, et al.
Published: (2004-02-01)

Efficient Synthesis of Boron-Containing α-Acyloxyamide Analogs via Microwave Irradiation
by: Po-Shen Pan, et al.
Published: (2013-08-01)

Genotoxicity evaluation of hydroalcoholic and aqueous extracts of Dorema aucheri by the comet assay
by: Mahmoud Etebari, et al.
Published: (2016-01-01)

Characterization of mitochondrial iron uptake in HepG2 cells
by: DORA INÉS MAZARIEGOS, et al.
Published: (2006-01-01)

Transcriptional Activation of Stress Genes and Cytotoxicity in Human Liver Carcinoma (HepG2) Cells Exposed to Pentachlorophenol
by: Elaine Shen, et al.
Published: (2002-09-01)

Ethanol extracts of Balanophora laxiflora Hemsl inhibit hepatocellular carcinoma with the involvement of HKII-mediated glycolysis
by: Dan Liu, et al.
Published: (2021-12-01)

Strigol1/albumin/chitosan nanoparticles decrease cell viability, induce apoptosis and alter metabolomics profile in HepG2 cancer cell line
by: Abdulrahman L. Al-Malki, et al.
Published: (2021-10-01)

Estudo da genotoxicidade e citotoxicidade da indometacina nanoencapsulada in vitro
by: Froder, Juliano Gabriel [UNESP]
Published: (2017)

Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid1
by: Andre Theriault, et al.
Published: (2000-12-01)

Comparative assessment of polyphenolics’ content, free radicals’ scavenging and cellular antioxidant potential in apricot fruit
by: Iqra Saeed, et al.
Published: (2021-07-01)