Estudo da expressão dos genes TETs e níveis de hidroximetilação em meduloblastoma

Estudo da expressão dos genes TETs e níveis de hidroximetilação em meduloblastoma

O meduloblastoma (MB) é um tumor embrionário que se origina de alterações genéticas em vias importantes para neurôgenese do cerebelo como Sonic hedgehog (Shh) e Wingless (Wnt). Alterações específicas nessas vias permitem a classificação do MB pelo perfil de expressão e mutacional em quatro subgrupos...

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Bibliographic Details
Main Author:	Salomão, Karina Bezerra
Other Authors:	Tone, Luiz Gonzaga
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2017
Subjects:	5-Hydroxymethylation Hidroximetilação IDH Medulloblastoma Meduloblastoma TET
Online Access:	http://www.teses.usp.br/teses/disponiveis/17/17135/tde-18042018-104554/

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