Secreção de Gaussia luciferase como indicador de atividade de caspase-3/7 em resposta ao tratamento com AdCDKN2AIRESp53 em glioblastoma multiforme.

Secreção de Gaussia luciferase como indicador de atividade de caspase-3/7 em resposta ao tratamento com AdCDKN2AIRESp53 em glioblastoma multiforme.

Este trabalho descreve a remediação simultânea de dois genes supressores de tumor, CDKN2A e p53, em três linhagens celulares derivadas de glioblastoma multiforme: U87 (CDKN2A-/-, p53wt/wt), U251 (CDKN2A-/-, p53mut/mut) e T98G (CDKN2A-/-, p53mut/mut). A entrega gênica foi mediada por vetor adenoviral...

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Bibliographic Details
Main Author:	Oliveira, Daniel Vieira Conde
Other Authors:	Strauss, Eugenia Costanzi
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2018
Subjects:	Adenovirus Adenovírus Cancer Câncer Gene therapy Genes supressores de tumor Luciferase Terapia gênica Tumor suppressor genes
Online Access:	http://www.teses.usp.br/teses/disponiveis/42/42134/tde-18022019-101454/

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