Produção de biblioteca de compostos derivados de produtos naturais: síntese e estudo de atividades biológicas

Produção de biblioteca de compostos derivados de produtos naturais: síntese e estudo de atividades biológicas

O presente trabalho trata da semissíntese de análogos de importantes compostos líderes (afidicolina, lausona, lapachol e CAPE) utilizando técnicas de química medicinal como bioisosterismo, adição de grupamento funcional e simplificação molecular. Dessa forma foi possível obter uma biblioteca de anál...

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Bibliographic Details
Main Author:	Mello, Rodrigo Brito de
Other Authors:	Emery, Flavio da Silva
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2014
Subjects:	Afidicolina Aphidicolin Bioisosterism Bioisosterismo Caffeic acid phenethyl ester Fenetil éster do ácido cafeico Molecular simplification Naftoquinonas Naftoquinones Natural products Produtos naturais Simplificação molecular
Online Access:	http://www.teses.usp.br/teses/disponiveis/60/60138/tde-17042015-151409/

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