Uso de RNA de interferência (siRNA) para modulação da expressão das moléculas co-estimuladoras CD80 e CD86 em células dendríticas.

Uso de RNA de interferência (siRNA) para modulação da expressão das moléculas co-estimuladoras CD80 e CD86 em células dendríticas.

As moléculas co-estimuladoras CD80 e CD86, expressas na superfície de células dendríticas (DCs), as principais células apresentadoras de antígenos profissionais (APCs), possuem participação fundamental na indução de resposta e manutenção de tolerância, motivo pelo qual são consideradas alvos terapêu...

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Bibliographic Details
Main Author:	Migliori, Isabella Katz
Other Authors:	Barbuto, Jose Alexandre Marzagao
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2010
Subjects:	Adjuvantes imunológicos Biologia celular CD80 CD86 Cell biology Células dendríticas Costimulatory molecules Dendritic cells Immunological adjuvants Imune modulation Imuno-modulação Moléculas co-estimuladoras RNA de interferência Small interfering RNA
Online Access:	http://www.teses.usp.br/teses/disponiveis/42/42133/tde-12012011-130147/

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