Ensaios celulares para a determinação da atividade citotóxica de moléculas antineoplásicas

Ensaios celulares para a determinação da atividade citotóxica de moléculas antineoplásicas

A pesquisa de substâncias bioativas apresenta diversas etapas de grande complexidade técnico-científica e envolve uma atividade multidisciplinar. No estudo de antineoplásicos, dentre outros candidatos a fármacos, a determinação do perfil de atividade biológica é um ponto essencial para a determinaçã...

Full description

Bibliographic Details
Main Author:	Saidel, Marta Érica
Other Authors:	Leitão, Andrei
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2016
Subjects:	câncer de próstata cellular assays ensaios celulares mTOR MTT prostate câncer
Online Access:	http://www.teses.usp.br/teses/disponiveis/75/75133/tde-08022017-152244/

Similar Items

Ensaios celulares para a determinação da atividade citotóxica de moléculas antineoplásicas
by: Marta Érica Saidel
Published: (2016)

Mechanistic Target of Rapamycin (mTOR) in the Cancer Setting
by: James T. Murray, et al.
Published: (2018-05-01)

Cyclic AMP-dependent signal transduction leading to mitogenesis in thyroid. Implication of the mammalian target of rapamycin (mTOR).
by: Blancquaert, Sara
Published: (2010)

Avaliação da expressão gênica e protéica da via mTOR/4EBP1/eIF4E nos carcinomas prostáticos caninos
by: Rivera Calderón, Luis Gabriel
Published: (2018)

mTOR signaling pathway and mTOR inhibitors in the treatment of cancer
by: Mehmet Küçüköner, et al.
Published: (2013-03-01)

mTOR Pathways in Cancer and Autophagy
by: Mathieu Paquette, et al.
Published: (2018-01-01)

Combining mTOR Inhibitors and T Cell-Based Immunotherapies in Cancer Treatment
by: Alexandre el Hage, et al.
Published: (2021-03-01)

Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention
by: Nazanin Momeni Roudsari, et al.
Published: (2021-08-01)

Metformin induces degradation of mTOR protein in breast cancer cells
by: Mohamed Alalem, et al.
Published: (2016-11-01)

Second Generation mTOR Inhibitors as a Double-Edged Sword in Malignant Glioma Treatment
by: Dennis Heinzen, et al.
Published: (2019-09-01)

Developing Viral Strategies to Study mTOR and its Regulators as Mediators of Epileptogenesis
by: Gulati, Ruhi
Published: (2019)

The role of RICTOR downstream of receptor tyrosine kinase in cancers
by: Ahlem Jebali, et al.
Published: (2018-02-01)

mTOR Promotes Tissue Factor Expression and Activity in EGFR-Mutant Cancer
by: Ying Cong, et al.
Published: (2020-08-01)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
by: Zhilin Zou, et al.
Published: (2020-03-01)

Efeito agudo de diferentes velocidades de exercício excêntrico na sinalização da hipertrofia muscular
by: Hamilton Augusto Roschel da Silva
Published: (2009)

Efeito agudo de diferentes velocidades de exercício excêntrico na sinalização da hipertrofia muscular
by: Silva, Hamilton Augusto Roschel da
Published: (2009)

Casticin-Induced Inhibition of Cell Growth and Survival Are Mediated through the Dual Modulation of Akt/mTOR Signaling Cascade
by: Jong Hyun Lee, et al.
Published: (2019-02-01)

mTOR Inhibitors in Advanced Biliary Tract Cancers
by: Chao-En Wu, et al.
Published: (2019-01-01)

The mTOR Signalling Pathway in Human Cancer
by: Paula Soares, et al.
Published: (2012-02-01)

Targeting the PI3K/Akt/mTOR Signaling Pathway: Applications of Nanotechnology
by: Forough Alemi Serej, et al.
Published: (2018-01-01)

Metformin – its potential anti-cancer and anti-aging effects
by: Monika Podhorecka, et al.
Published: (2017-03-01)

Targeting the Mammalian Target of Rapamycin (mTOR) in Cancer Therapy: Lessons from Past and Future Perspectives
by: Olivier Dormond, et al.
Published: (2011-05-01)

mTOR Signaling Pathway in Cancer Targets Photodynamic Therapy In Vitro
by: Sandra M. Ayuk, et al.
Published: (2019-05-01)

Rhein Suppresses Colorectal Cancer Cell Growth by Inhibiting the mTOR Pathway In Vitro and In Vivo
by: Haibo Zhang, et al.
Published: (2021-04-01)

mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership
by: Angel Cayo, et al.
Published: (2021-07-01)

Metformin extends C. elegans lifespan through lysosomal pathway
by: Jie Chen, et al.
Published: (2017-10-01)

Regulation of mTORC1 by lysosomal calcium and calmodulin
by: Ruo-Jing Li, et al.
Published: (2016-10-01)

mTOR pathway somatic variants and the molecular pathogenesis of hemimegalencephaly
by: Camila A. B. Garcia, et al.
Published: (2020-03-01)

Everolimus for the treatment of refractory seizures associated with tuberous sclerosis complex (TSC): current perspectives
by: Overwater IE, et al.
Published: (2019-07-01)

Stalling autophagy: a new function for Listeria phospholipases
by: Ivan Tattoli, et al.
Published: (2014-01-01)

Targeting mTOR as a Therapeutic Approach in Medulloblastoma
by: Juncal Aldaregia, et al.
Published: (2018-06-01)

Rosemary (Rosmarinus officinalis L.) extract inhibits prostate cancer cell proliferation and survival by targeting Akt and mTOR
by: Alina Jaglanian, et al.
Published: (2020-11-01)

Corrigendum: Dual-mTOR Inhibitor Rapalink-1 Reduces Prostate Cancer Patient-Derived Xenograft Growth and Alters Tumor Heterogeneity
by: Federico La Manna, et al.
Published: (2021-02-01)

Dual-mTOR Inhibitor Rapalink-1 Reduces Prostate Cancer Patient-Derived Xenograft Growth and Alters Tumor Heterogeneity
by: Federico La Manna, et al.
Published: (2020-06-01)

HDAC Inhibition Counteracts Metastatic Re-Activation of Prostate Cancer Cells Induced by Chronic mTOR Suppression
by: Jasmina Makarević, et al.
Published: (2018-09-01)

LncRNA HULC mediates radioresistance via autophagy in prostate cancer cells
by: Changxuan Chen, et al.
Published: (2018-04-01)

Dose-dependent Effects of mTOR Inhibition on Weight and Mitochondrial Disease in Mice
by: Simon C Johnson, et al.
Published: (2015-07-01)

Overreaching não funcional em modelo animal: adaptações inflamatórias e hipertróficas do músculo cardíaco
by: Alisson Luiz da Rocha
Published: (2017)

Overreaching não funcional em modelo animal: adaptações inflamatórias e hipertróficas do músculo cardíaco
by: Rocha, Alisson Luiz da
Published: (2017)

Estudo do envolvimento da proteína colibistina no controle do início da tradução
by: Camila de Oliveira Freitas Machado
Published: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kfhvqmqqjimcfnsqn0o82qcvfn