Descoberta de ligantes do receptor de melanocortina-5 (MC5R) como candidatos a moduladores da sebogênese: estudos de modelagem por homologia, triagem virtual e ensaio celular

Descoberta de ligantes do receptor de melanocortina-5 (MC5R) como candidatos a moduladores da sebogênese: estudos de modelagem por homologia, triagem virtual e ensaio celular

A acne é uma condição da pele multifatorial com implicações socioeconômicas importantes. Um dos principais fatores que contribuem com a sua etiologia é a superprodução de sebo. Até o momento, há poucos tratamentos seguros e eficazes disponíveis. O receptor de melanocortina-5 (MC5R), um receptor acop...

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Bibliographic Details
Main Author:	Katekawa, Edson
Other Authors:	Guido, Rafael Victório Carvalho
Format:	Others
Language:	pt
Published:	Biblioteca Digitais de Teses e Dissertações da USP 2018
Subjects:	G-protein coupled receptor Homology modeling Melanocortin receptor Modelagem por homologia Receptor acoplado à proteína G Receptor de melanocortina Sebogênese Sebogenesis Structure-based virtual screening Triagem virtual baseada em estrutura
Online Access:	http://www.teses.usp.br/teses/disponiveis/76/76132/tde-03052019-102237/

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