Modulation of tumor necrosis factor related apoptosis-inducing ligand (trail) receptors in a human osteoclast model in vitro

We have previously shown that osteoclasts (OCLs) from multiple myeloma (MM) specimens vary from healthy OCLs in their expression of the TRAIL receptors. TRAIL (TNF-Related Apoptosis-Inducing Ligand), a member of the TNF superfamily, has been shown to induce apoptosis in cells by binding receptors DR...

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Bibliographic Details
Main Author: McManus, Stephen
Other Authors: Roux, Sophie
Language:English
Published: Université de Sherbrooke 2010
Subjects:
Online Access:http://savoirs.usherbrooke.ca/handle/11143/4077