Involvement of the Sigma-1 Receptor in Neuronal Cell Death and Alzheimer's Disease

Dysfunction in the Sigma-1 receptor (Sig-1R) is implicated in many neurodegenerative diseases such as Alzheimer’s Disease (AD). Recently, agonists of the Sig-1R have been found to be neuroprotective in AD and provide significant improvements in symptoms. The hallmarks of AD are aggregation of amyloi...

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Bibliographic Details
Main Author: Raymond, Sophie Olivia
Other Authors: Bergeron, Richard
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2021
Subjects:
Online Access:http://hdl.handle.net/10393/42698
http://dx.doi.org/10.20381/ruor-26917