Characterization of HIV-1 Proviral Latency Induced Through APOBEC3 Mutagenesis and Reverse Transcriptase Error
Human Immunodeficiency Virus 1 (HIV-1) is a lentivirus that forms persistent latently infected reservoirs that are the remaining major hurdle for current HIV-1 treatments. APOBEC3 (A3) proteins are intrinsic retroviral restriction factors that introduce GA mutations during reverse transcription, wh...
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| Format: | Others |
| Language: | en |
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Université d'Ottawa / University of Ottawa
2020
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| Online Access: | http://hdl.handle.net/10393/41078 http://dx.doi.org/10.20381/ruor-25302 |