The Role of Sigma-1 Receptor in Modulating Endoplasmic Reticulum Stress: Putative Relevance to Alzheimer Disease
Alzheimer’s Disease and other neurodegenerative diseases have been linked to dysfunction in proteostasis in the endoplasmic reticulum (ER). The ER provides an exclusive environment for protein synthesis and folding, which is vital to the cellular function. Under normal conditions, the synthesis and...
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| Format: | Others |
| Language: | en |
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Université d'Ottawa / University of Ottawa
2018
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| Online Access: | http://hdl.handle.net/10393/38395 http://dx.doi.org/10.20381/ruor-22648 |