Investigating Lipidomic Determinants of Cognitive Impairment in Mouse Models of Alzheimer’s Disease

Investigating Lipidomic Determinants of Cognitive Impairment in Mouse Models of Alzheimer’s Disease

Alzheimer’s disease is an insidious neurodegenerative disease that affects millions of people worldwide. Currently, there are no determinants that can accurately predict the onset cognitive decline in AD. This thesis investigates and defines changes in the lipidome that are linked to symptomatic ons...

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Bibliographic Details
Main Author:	Granger, Matthew
Other Authors:	Bennett, Steffany A.L.
Format:	Others
Language:	en
Published:	Université d'Ottawa / University of Ottawa 2018
Subjects:	Alzheimer's disease Neurolipidomics Mouse models Morris Water Maze Learning and memory Search strategy Mass spectrometry Cognitive reserve
Online Access:	http://hdl.handle.net/10393/37984 http://dx.doi.org/10.20381/ruor-22241

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