The Role of p130/DREAM in Silencing Self-renewal Genes in Post-mitotic Neurons.
The recently identified DREAM complex assembles when Rb-like protein (p130, p107) recruits E2F4, DP (dimerization partner) and MuvB (multivulval complex B (Lin9, Lin37, Lin52, Lin54, and RbBp4)) during G0 and quiescence to repress cell cycle-dependent genes. DREAM assembly requires phosphorylation o...
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Format: | Others |
Language: | en |
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Université d'Ottawa / University of Ottawa
2018
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Online Access: | http://hdl.handle.net/10393/37719 http://dx.doi.org/10.20381/ruor-21983 |