The Role of p130/DREAM in Silencing Self-renewal Genes in Post-mitotic Neurons.

The recently identified DREAM complex assembles when Rb-like protein (p130, p107) recruits E2F4, DP (dimerization partner) and MuvB (multivulval complex B (Lin9, Lin37, Lin52, Lin54, and RbBp4)) during G0 and quiescence to repress cell cycle-dependent genes. DREAM assembly requires phosphorylation o...

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Bibliographic Details
Main Author: Azzi, Joelle
Other Authors: Slack, Ruth
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2018
Subjects:
Online Access:http://hdl.handle.net/10393/37719
http://dx.doi.org/10.20381/ruor-21983