β1 Integrin Regulates PC3 Prostate Cancer Cell Phenotypes in part via Regulation of Matricellular SPARC

We have shown herein that β1 integrin stably depleted PC3 sub-clonal cells confer a trend towards increased survival of mice compared to β1 integrin expressing counterparts when tested in an intracardial bone metastasis model. Therefore, we sought to investigate novel factors that mediate β1 integri...

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Bibliographic Details
Main Author: Bugiel, Steven
Other Authors: Addison, Christina
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
Online Access:http://hdl.handle.net/10393/34785
http://dx.doi.org/10.20381/ruor-891