Characterization of Surgery-Induced Vaccine Dysfunction in a Therapeutic Murine Melanoma Model
Surgical resection is the leading treatment of most solid tumours, however surgical stress creates an immunosuppressive environment that promotes metastases. A global decrease in T cell numbers and function post-surgery has been documented. However, the effect on tumour associated antigen (TAA)-spec...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2016
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| Online Access: | http://hdl.handle.net/10393/34269 http://dx.doi.org/10.20381/ruor-5627 |