Expression Levels of E-cadherin in Breast Cancer Cells Alter Apoptotic Susceptibility and Facilitate Cancer Stem Cell Phenotypes in Response to Wnt Signalling

It is well established that the Wnt pathway is associated with tumorigenesis in a wide range of human cancers, including a majority of breast cancers. However, due to diverse roles of Wnt signalling, therapeutic targeting has not yielded consistent results and underlying mechanisms remain unclear. H...

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Bibliographic Details
Main Author: Ooi, Sarah
Other Authors: Wang, Lisheng
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
Wnt
Akt
Online Access:http://hdl.handle.net/10393/32961
http://dx.doi.org/10.20381/ruor-1490

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