Characterization of [18F]FPyKYNE-Losartan as a Novel PET Tracer for Imaging AT1 Receptors

The Angiotensin II Type I Receptor (AT1R) is the main receptor that produces most of the physiological actions of the Renin Angiotensin System (RAS). Alterations of AT1R expression in renal and cardiovascular diseases make this receptor an attractive target for developing an imaging agent to monitor...

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Bibliographic Details
Main Author: Hachem, Maryam
Other Authors: DaSilva, Jean
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
RAS
PET
Online Access:http://hdl.handle.net/10393/32417
http://dx.doi.org/10.20381/ruor-4362

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