Molecular Mechanism Involved in HIV-Tat Mediated inhibition of LPS-Induced IL-23 and IL-27 Production in Human Macrophages
Monocyte-derived macrophages (MDMs) from HIV-infected patients and MDMs infected in vitro with HIV manifest inhibition of various cytokines including IL 12. Recently, IL-27 was shown to inhibit HIV replication in macrophages. Whether HIV infection or HIV regulatory proteins such as tat, impact IL-23...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2015
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| Online Access: | http://hdl.handle.net/10393/32300 http://dx.doi.org/10.20381/ruor-3938 |