Synthesis of Homo A-CD Estrogens for Potential Use in Hormone Replacement Therapy
Hormone replacement therapy (HRT) has been subject to much debate due to concerns that long term use of such treatment of menopause increases the risk of breast and uterine cancer. This is thought to be caused by estradiol (1) binding to the estrogen receptor α (ERα) resulting in increased cell prol...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2015
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| Online Access: | http://hdl.handle.net/10393/32082 http://dx.doi.org/10.20381/ruor-2783 |