Regions of the CD127 Cytoplasmic Tail Necessary for HIV-1 Tat Binding

Impaired cell mediated immunity is the clinical hallmark of HIV infection yet the manner in which CD8 T-cells are disabled is not yet fully understood. IL-7 signalling is essential for normal CD8 T-cell development and function. Our lab has previously shown decreased expression of the IL-7 receptor...

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Bibliographic Details
Main Author: Cherid, Hafsa
Other Authors: MacPherson, Paul
Language:en
Published: Université d'Ottawa / University of Ottawa 2014
Subjects:
Online Access:http://hdl.handle.net/10393/31556
http://dx.doi.org/10.20381/ruor-6643