Effects of Acute and Sustained Administration of Vilazodone (EMD68843) on Monoaminergic Systems: An In Vivo Electrophysiological Study

Vilazodone is a partial 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor (SSRI). Acute administration caused a dose-dependent decrease in dorsal raphe (DR) serotonin (5-HT) neuron firing rates. Vilazodone significantly decreased DR 5-HT neuronal firing following 2-day administrat...

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Bibliographic Details
Main Author: Crnic, Agnes
Other Authors: Blier, Pierre
Language:en
Published: Université d'Ottawa / University of Ottawa 2014
Subjects:
Online Access:http://hdl.handle.net/10393/31498
http://dx.doi.org/10.20381/ruor-6628

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