Functional Studies of Dopamine-D2S Receptor Signaling through the RASA3 Pathway

RASA3 (Ras p21 GTPase Activating Protein 3) is required for D2SR (Dopamine D2 Short Receptor) induced ERK1/2 inhibition in pituitary lactotroph GH4ZR7 cells. We hypothesized that RASA3 may be important for D2SR signaling to inhibit ERK1/2 in dopamine neurons, and thus negatively regulate TH (Tyrosin...

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Bibliographic Details
Main Author: Chang, Chao
Other Authors: Albert, Paul
Language:en
Published: Université d'Ottawa / University of Ottawa 2014
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Online Access:http://hdl.handle.net/10393/31442
http://dx.doi.org/10.20381/ruor-6329