MiR-145 Plays a Role in Oligodendroyte Differentiation by Regulating Cytoskeleton- and Myelin-Related Gene Expression
A key problem in multiple sclerosis (MS) is the diminished capacity for myelin repair. Although oligodendrocyte (OL) precursors can be seen at the lesion site, their ability to differentiate appears inhibited. MicroRNAs are key regulators of OL differentiation, and have been observed to be misregula...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2014
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| Online Access: | http://hdl.handle.net/10393/30512 http://dx.doi.org/10.20381/ruor-6687 |