Electrophysiological Investigations on the Role of Selected Serotonin Receptors and the Serotonin Transporter on Serotonin Transmission in the Rat Brain

Electrophysiological Investigations on the Role of Selected Serotonin Receptors and the Serotonin Transporter on Serotonin Transmission in the Rat Brain

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This study assessed the in vivo effects of various serotonin (5-HT) receptor modulators on 5-HT neurotransmission in the rat hippocampus. Vortioxetine, humanized-vortioxetine, and escitalopram blocked the 5-HT transporter, but similar to ipsapirone did not dampen the sensitivity of postsynaptic 5-HT...

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Bibliographic Details
Main Author:	Lecours, Maurice
Other Authors:	Blier, Pierre
Language:	en
Published:	Université d'Ottawa / University of Ottawa 2014
Subjects:	Depression Vortioxetine Hippocampus Electrophysiology Serotonin Lu AA21004 Multimodal Antidepressant
Online Access:	http://hdl.handle.net/10393/30400 http://dx.doi.org/10.20381/ruor-3484

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