The eIF4E2-Mediated Hypoxic Protein Synthesis Complex Permits Tumourigenesis in Several Genetically Distinct Cancers
Identifying exploitable differences between cancer cells and normal cells has been ongoing since the dawn of cancer therapeutics. This task has proven difficult due to the complex genetic makeup of cancers. Tumours, however, share a low oxygen (hypoxic) microenvironment that selects for malignant ca...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2013
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| Online Access: | http://hdl.handle.net/10393/26198 http://dx.doi.org/10.20381/ruor-6691 |