Podocyte-specific Overexpression of Human Angiotensin-converting Enzyme 2 Attenuates Diabetic Nephropathy in Mice

Podocyte-specific Overexpression of Human Angiotensin-converting Enzyme 2 Attenuates Diabetic Nephropathy in Mice

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Angiotensin-converting enzyme 2 (ACE2) is an important component of the renin-angiotensin system (RAS). ACE2 is thought to have a renoprotective effect in diabetic nephropathy because it is capable of degrading profibrotic angiotensin II to potentially protective angiotensin-(1-7). Podocyte death an...

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Bibliographic Details
Main Author: Bose, Renisha Padmini
Other Authors: Burns, Kevin
Language:en
Published: Université d'Ottawa / University of Ottawa 2013
Subjects:
ACE2
podocyte
diabetes
angiotensin
albuminuria
Online Access:http://hdl.handle.net/10393/23776
http://dx.doi.org/10.20381/ruor-6437

Internet

http://hdl.handle.net/10393/23776
http://dx.doi.org/10.20381/ruor-6437

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