Potentiating the Oncolytic Efficacy of Poxviruses
Several wild-type poxviruses have emerged as potential oncolytic viruses (OVs), including orf virus (OrfV), and vaccinia virus (VV). Oncolytic VVs have been modified to include attenuating mutations that enhance their tumour selective nature, but these mutations also reduce overall viral fitness in...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2012
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| Online Access: | http://hdl.handle.net/10393/23114 http://dx.doi.org/10.20381/ruor-5285 |