Comprehensive Model of G Protein-coupled Receptor Regulation by Protein Kinase C: Insight from Dopamine D1 and D5 Receptor Studies.

Comprehensive Model of G Protein-coupled Receptor Regulation by Protein Kinase C: Insight from Dopamine D1 and D5 Receptor Studies.

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Dopamine receptors belong to the G protein-coupled receptor (GPCR) superfamily and are classified into two families: D1-like (D1R and D5R) and D2-like (D2R, D3R and D4R), based on their ability to stimulate or inhibit adenylyl cyclase (AC). Classically, GPCRs (including D2R and D3R) are desensitized...

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Bibliographic Details
Main Author: Plouffe, Bianca
Other Authors: Albert, Paul R.
Language:en
Published: Université d'Ottawa / University of Ottawa 2012
Subjects:
dopamine
protein kinase C
D1-like dopaminergic receptors
D1 receptor
D5 receptor
desensitization
sensitization
Online Access:http://hdl.handle.net/10393/20577
http://dx.doi.org/10.20381/ruor-3527

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