DNA Methylation, Cellular Stress Response and Expression of Inner Nuclear Membrane Proteins

DNA Methylation, Cellular Stress Response and Expression of Inner Nuclear Membrane Proteins

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Hutchinson-Gilford Progeria Syndrome is described as a series of mutations within the lamin A gene leading to the accumulation of progerin in the nucleus, contributing to premature aging and affecting the epigenetic control. Epigenetic control, such as DNA methylation, relies on DNA methyltransferas...

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Bibliographic Details
Main Author: Levesque, Steve
Other Authors: Paulin-Levasseur, Micheline
Language:en
Published: Université d'Ottawa / University of Ottawa 2011
Subjects:
Epigenetics
DNA methylation
Nuclear stress bodies
Inner nuclear membrane (INM)
Lamin A
Lamin B
Emerin
Satellite III (Sat III)
Stress response
Heat shock (HS)
2H12
Lamina associated polypeptide 2 (Lap2)
Fibrillarin
Laminopathies
Hutchinson Gilford Progeria Syndrome (HGPS)
Online Access:http://hdl.handle.net/10393/19949
http://dx.doi.org/10.20381/ruor-4565
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