Synthesis of Non-Steroidal Estrogen Agonists for Hormone Replacement Therapy and Synthesis and Reactivity of 2,3-Substituted 5-Silyl-7-Oxa-Bicyclo[2.2.1]Heptenes and Heptadienes
The focus of the research described in this section of the thesis is the synthesis of compounds expected to bind strongly to both the estrogen β and α receptors and act as estrogen agonists. Based on earlier results in our group and docking studies we prepared a series of A-CD analogs, compounds 1,...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2011
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| Online Access: | http://hdl.handle.net/10393/19750 http://dx.doi.org/10.20381/ruor-5470 |