| Summary: | xvii, 245 p. : ill. A print copy of this thesis is available through the UO Libraries. Search the library catalog for the location and call number. === There has been a lot of research investigating the effects of heat stress and exercise on the physiological adaptations to heat acclimation. It is well documented that heat acclimation improves heat tolerance and performance in a hot environment; however, some of the mechanisms of adaptation are not clear. Furthermore, the role of heat acclimation on exercise performance in cool environments is currently unknown. Therefore, in Chapter IV we aimed to determine the effects of heat acclimation on lactate threshold and maximal oxygen uptake (VO 2max ) in cool and hot conditions. We also sought to investigate the effects of heat acclimation on leg blood flow and oxygen delivery during a single-leg knee extensor exercise. We found that heat acclimation improved lactate threshold and VO 2max in cool and hot environments but did not alter the leg blood flow and oxygen delivery during the leg kicking exercise. In Chapter V we investigated the heat acclimation effects on performance during a 1-hour time trial in hot and cool environmental conditions and the potential mechanisms by which this occurs. A secondary objective was to study whether the pacing strategy was modified during the time trial post-heat acclimation. The results demonstrated that heat acclimation improved time trial performance in both thermal environments by approximately 7% but pacing strategy was not altered. The purpose of the studies in Chapter VI were twofold. First, we sought to investigate how heat acclimation affects the skin blood flow and sweating responses to pharmacological treatment with specific dosages of the muscarinic receptor agonist acetylcholine. Second, we examined the maximal skin blood flow responses to a period of heat acclimation by locally heating the forearm with a water spray device for 45 minutes and measured brachial artery blood flow via ultrasound. We found that heat acclimation increased sweat rate and skin blood flow responses to given concentrations of acetylcholine, suggesting a role for peripheral mechanisms. On the other hand, maximal skin blood flow remained unchanged after heat acclimation. === Committee in charge: Christopher Minson, Chairperson, Human Physiology;
John Halliwill, Member, Human Physiology;
Andrew Lovering, Member, Human Physiology;
Michael Sawka, Member, Not from U of 0;
Scott Frey, Outside Member, Psychology
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