Investigating the Mechanisms involved in Traffic-Generated Air Pollution: Mediated Disruption of the Blood-Brain Barrier in a Wild Type Mouse Model using a Pharmaceutical Intervention Approach

Investigating the Mechanisms involved in Traffic-Generated Air Pollution: Mediated Disruption of the Blood-Brain Barrier in a Wild Type Mouse Model using a Pharmaceutical Intervention Approach

This study investigated whether oxLDL and/or angiotensin (Ang) II signaling pathways mediate traffic-generated air pollution- exposure induced alterations in blood-brain barrier (BBB) integrity and permeability in a healthy wild type (C57Bl/6) mouse model; additionally, whether these outcomes are ex...

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Bibliographic Details
Main Author: Suwannasual, Usa
Other Authors: Lund, Amie
Format: Others
Language:English
Published: University of North Texas 2020
Subjects:
Traffic pollution,
Oxidized low density lipoprotein,
Lectin-like oxidized LDL receptor,
Angiotensin II type 1 receptor,
Cerebral microvessel
Online Access:https://digital.library.unt.edu/ark:/67531/metadc1707379/

Internet

https://digital.library.unt.edu/ark:/67531/metadc1707379/

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