Effects of Rhes Prenylation on Mouse Cognition in a 3-Nitropropionic Acid Animal Model of Huntington's Disease

Effects of Rhes Prenylation on Mouse Cognition in a 3-Nitropropionic Acid Animal Model of Huntington's Disease

Located on the short arm of chromosome 4, there exists a gene, IT15, responsible for the trinucleotide CAG expansion involved in the autosomal dominant neurodegenerative disorder known as Huntington’s disease (HD). The brain region associated with the most atrophy, the striatum, leads to expression...

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Bibliographic Details
Main Author: Hobbs, Diana
Format: Others
Published: ScholarWorks@UNO 2015
Subjects:
Huntington’s disease
Rhes
prenylation
statins
bisphosphonates
cognition
Animal Studies
Biological Psychology
Online Access:http://scholarworks.uno.edu/td/1977
http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=3031&context=td

Internet

http://scholarworks.uno.edu/td/1977
http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=3031&context=td

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