The effects of chronic simvastatin treatment on the expression of behavioral symptoms in a transgenic mouse model of Huntington’s disease

The effects of chronic simvastatin treatment on the expression of behavioral symptoms in a transgenic mouse model of Huntington’s disease

Huntington’s disease (HD) is a heritable, neurodegenerative disorder characterized by motor, cognitive, and psychiatric disturbances. An unstable CAG expansion within the gene normally encoding for the Huntingtin protein is responsible. The expanded mutant form of Huntingtin and the putative protein...

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Bibliographic Details
Main Author: Whitmarsh, Ashley
Format: Others
Published: ScholarWorks@UNO 2013
Subjects:
Huntington's disease
Rhes
statin
mevalonate
Huntingtin protein
rotarod
Behavioral Neurobiology
Biochemistry
Biological Psychology
Online Access:http://scholarworks.uno.edu/td/1773
http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=2815&context=td

Internet

http://scholarworks.uno.edu/td/1773
http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=2815&context=td

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