Synthesis and Biological Evaluation of Novel GBR 12909 Tropane and Azetidine Hybrid Analogues
The high affinity, selective dopamine transporter ligand GBR 12909 has served as a template for the design of two novel classes of dopamine transporter ligands. A series of 3-[2- (diarylmethoxyethyidenyl)]-N-substituted tropane derivatives were synthesized and the binding affinities of these comp...
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Format: | Others |
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ScholarWorks@UNO
2007
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Online Access: | http://scholarworks.uno.edu/td/565 http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=1565&context=td |