Synthesis and Biological Evaluation of Novel GBR 12909 Tropane and Azetidine Hybrid Analogues

The high affinity, selective dopamine transporter ligand GBR 12909 has served as a template for the design of two novel classes of dopamine transporter ligands. A series of 3-[2- (diarylmethoxyethyidenyl)]-N-substituted tropane derivatives were synthesized and the binding affinities of these comp...

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Bibliographic Details
Main Author: Cararas, Shaine A.
Format: Others
Published: ScholarWorks@UNO 2007
Subjects:
Online Access:http://scholarworks.uno.edu/td/565
http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=1565&context=td