Relationship Between Chronic Inflammation and Cancer: Interleukin-1β Overexpression Induces Pancreatic Ductal Adenocarcinoma in Oncogenic Kras Mice
Chronic pancreatitis is an established risk factor for pancreatic ductal adenocarcinoma (PDAC) development. Polymorphisms in the pro-inflammatory cytokine gene interleukin 1β (IL-1β), as well as high IL-1β or low IL-1 receptor antagonist (IL-1RA) serum levels, are associated to worse prognosis in...
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| Format: | Doctoral Thesis |
| Language: | en |
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Alma Mater Studiorum - Università di Bologna
2016
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| Online Access: | http://amsdottorato.unibo.it/7316/ |