Inibizione selettiva del gene MYCN mediante PNA (acidi peptido nucleici) anti-gene nel rabdomiosarcoma umano
MYCN oncogene amplification/expression is a feature of many childhood tumors, and some adult tumors, and it is associated with poor prognosis. While MYC expression is ubiquitary, MYCN has a restricted expression after birth and it is an ideal target for an effective therapy. PNAs belong to the la...
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| Format: | Doctoral Thesis |
| Language: | it |
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Alma Mater Studiorum - Università di Bologna
2008
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| Online Access: | http://amsdottorato.unibo.it/690/ |