The role of mitochondria in the regulation of gamma rays induced mTOR-dependent senescence

The first aims of this study were to demonstrate if mitochondrial biogenesis and senescence can be induced simultaneously in cell lines upon exposure to a genotoxic stress, and if the presence of mtDNA mutations which impair the functionality of respiratory complexes can influence the ability of a...

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Bibliographic Details
Main Author: Mariani, Elisa <1982>
Other Authors: Romeo, Giovanni
Format: Doctoral Thesis
Language:en
Published: Alma Mater Studiorum - Università di Bologna 2012
Subjects:
Online Access:http://amsdottorato.unibo.it/4799/