The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease.
Skeletal muscle possesses the remarkable capacity to complete a rapid and extensive regeneration, even following severe damage. The regenerative ability of skeletal muscle relies on Satellite Cells (SCs), a population of muscle specific adult stem cells. However, during aging or under several pathol...
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ndltd-unibo.it-oai-amsdottorato.cib.unibo.it-42582014-03-24T16:29:44Z The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease. Scaramozza, Annarita <1982> BIO/16 Anatomia umana Skeletal muscle possesses the remarkable capacity to complete a rapid and extensive regeneration, even following severe damage. The regenerative ability of skeletal muscle relies on Satellite Cells (SCs), a population of muscle specific adult stem cells. However, during aging or under several pathological conditions, the ability of skeletal muscle to fully regenerated is compromised. Here, a morphological and molecular study on SCs from patients affected by ALS is described. Moreover, the role of the cell cycle regulator P16Ink4a during skeletal muscle regeneration and aging has been investigated. Alma Mater Studiorum - Università di Bologna Billi, Anna Maria 2012-01-16 Doctoral Thesis PeerReviewed application/pdf en http://amsdottorato.unibo.it/4258/ info:eu-repo/semantics/openAccess |
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Doctoral Thesis |
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BIO/16 Anatomia umana |
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BIO/16 Anatomia umana Scaramozza, Annarita <1982> The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease. |
description |
Skeletal muscle possesses the remarkable capacity to complete a rapid and extensive regeneration, even following severe damage. The regenerative ability of skeletal muscle relies on Satellite Cells (SCs), a population of muscle specific adult stem cells. However, during aging or under several pathological conditions, the ability of skeletal muscle to fully regenerated is compromised. Here, a morphological and molecular study on SCs from patients affected by ALS is described. Moreover, the role of the cell cycle regulator P16Ink4a during skeletal muscle regeneration and aging has been investigated. |
author2 |
Billi, Anna Maria |
author_facet |
Billi, Anna Maria Scaramozza, Annarita <1982> |
author |
Scaramozza, Annarita <1982> |
author_sort |
Scaramozza, Annarita <1982> |
title |
The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease. |
title_short |
The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease. |
title_full |
The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease. |
title_fullStr |
The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease. |
title_full_unstemmed |
The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease. |
title_sort |
regulation of satellite cells during skeletal muscle regeneration and neuromuscular disease. |
publisher |
Alma Mater Studiorum - Università di Bologna |
publishDate |
2012 |
url |
http://amsdottorato.unibo.it/4258/ |
work_keys_str_mv |
AT scaramozzaannarita1982 theregulationofsatellitecellsduringskeletalmuscleregenerationandneuromusculardisease AT scaramozzaannarita1982 regulationofsatellitecellsduringskeletalmuscleregenerationandneuromusculardisease |
_version_ |
1716654471880114176 |