Die Rolle der PDE3 im cGMP/cAMP-Crosstalk in NO-GC-defizienten Mäusen

Die Rolle der PDE3 im cGMP/cAMP-Crosstalk in NO-GC-defizienten Mäusen

Die NO-sensitive Guanylyl-Cyclase (NO-GC) ist der wichtigste Rezeptor für das freigesetzte Signalmolekül NO und katalysiert die Bildung des second Messenger cGMP. Die NO/cGMP Signalkaskade ist im kardiovaskulären System essentiell für die Hemmung der Thrombozytenaggregation und des Tonus der glatten...

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Bibliographic Details
Main Author:	Karlisch, Kaja
Format:	Doctoral Thesis
Language:	deu
Published:	2013
Subjects:	cGMP Gen-Knockout Guanylylcyclase ddc:610
Online Access:	https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/9885 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-98857 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-98857 https://opus.bibliothek.uni-wuerzburg.de/files/9885/Kaja_Karlisch_Dissertation.pdf

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