Regulation of TLR-induced macrophage responses by cytoskeleton-associated phosphoproteins

Toll-like receptors (TLR) are pattern recognition receptors (PRR) by which macrophages (MØ) sense pathogen-associated molecular patterns (PAMPs). The recognition of lipopolysaccharide (LPS), the PAMP of gram negative bacteria, by TLR4 triggers signaling cascades and leads to the pro-inflammatory act...

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Bibliographic Details
Main Author: Wenzel, Jens
Format: Doctoral Thesis
Language:English
Published: 2014
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/9884
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-98843
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-98843
https://opus.bibliothek.uni-wuerzburg.de/files/9884/Wenzel_Jens_PhD_thesis.pdf