Regulation of TLR-induced macrophage responses by cytoskeleton-associated phosphoproteins
Toll-like receptors (TLR) are pattern recognition receptors (PRR) by which macrophages (MØ) sense pathogen-associated molecular patterns (PAMPs). The recognition of lipopolysaccharide (LPS), the PAMP of gram negative bacteria, by TLR4 triggers signaling cascades and leads to the pro-inflammatory act...
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Format: | Doctoral Thesis |
Language: | English |
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2014
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Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/9884 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-98843 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-98843 https://opus.bibliothek.uni-wuerzburg.de/files/9884/Wenzel_Jens_PhD_thesis.pdf |